Model reference · open weights

Baichuan-M3

LLMs baichuan-inc Text gen 3 builds Open weights 5k dl/mo

Baichuan-M3 is an open-weight language model from baichuan-inc. Baichuan-M3-235B-GPTQ-INT4 (GPTQ) weighs 125 GB; the smallest configuration that runs it is H200 141 GB.

  • Baichuan-M3 is a 235.1B parameter medical-enhanced large language model developed by baichuan-inc for text generation tasks.
  • It supports English and Chinese with a context length of 40,960 tokens and is licensed under Apache-2.0.
  • The model is specifically trained to model clinical decision-making processes, including high-fidelity clinical inquiry and systematic hallucination constraints.

Summary of the baichuan-inc/Baichuan-M3-235B-GPTQ-INT4 model card, 2026-10-01

What it is

Released bybaichuan-inc
Released2026-01-13
Parameters235.1B
VRAM125 GB for the weights

What it runs on

Memory and cards for Baichuan-M3-235B-GPTQ-INT4 (GPTQ)

125 GBweights, file size
193 MBcache per 1K tokens
1.7 GBruntime overhead, at least
40,960 tokenscontext max
CardRequests at onceContext maxMemory
8K each32K each
RTX 3060 12 GB … DGX Spark (GB10) 128 GB unified
10 smaller cards
———
H200 141 GB2—23K138 GB
B200 180 GB246all 40K176 GB
2× H100 80 GB
tensor parallel
82all 40K78.1 GB a card
2× A100 80 GB
tensor parallel
184all 40K78.2 GB a card
4× L40S 48 GB
tensor parallel
287all 40K44.0 GB a card
2× RTX PRO 6000 Blackwell 96 GB
tensor parallel
287all 40K93.8 GB a card
2× H200 141 GB
tensor parallel
8421all 40K138 GB a card
Memory needed at each load
Requests at once8K tokens each32K tokens each
1128 GB133 GB
5134 GB158 GB
8139 GB177 GB
16151 GB227 GB
32177 GB328 GB
64227 GB530 GB

One card, with vLLM's small-card settings.

Builds

Sizes, precisions & builds

BuildParamsPrecisionWeightsSmallest setup
Baichuan-M3-235B-GPTQ-INT4 (above) ↗ 235.1BGPTQ 125 GBH200 141 GB
Baichuan-M3-235B ↗ 235.1BBF16 470 GB4× H200 141 GB
Baichuan-M3-235B-FP8 ↗ 235.1BFP8 236 GB2× H200 141 GB

From the model card

What baichuan-inc says about Baichuan-M3

Read the model card

From Inquiry to Decision: Building Trustworthy Medical AI

🏥 Experience AI-Powered Medical Inquiry: ying.ai

🌟 Model Overview

Baichuan-M3 is Baichuan AI's new-generation medical-enhanced large language model, a major milestone following Baichuan-M2.

In contrast to prior approaches that primarily focus on static question answering or superficial role-playing, Baichuan-M3 is trained to explicitly model the clinical decision-making process, aiming to improve usability and reliability in real-world medical practice. Rather than merely producing "plausible-sounding answers" or high-frequency vague recommendations like "you should see a doctor soon," the model is trained to proactively acquire critical clinical information, construct coherent medical reasoning pathways, and systematically constrain hallucination-prone behaviors.

Core Highlights

  • 🏆 Surpasses GPT-5.2: Outperforms OpenAI's latest model across HealthBench, HealthBench-Hard, hallucination evaluation, and SCAN-bench, establishing a new SOTA in medical AI
  • 🩺 High-Fidelity Clinical Inquiry: The only model to rank first across all three SCAN-bench dimensions—Clinical Inquiry, Laboratory Testing, and Diagnosis
  • 🧠 Low Hallucination, High Reliability: Achieves lower hallucination rates than GPT-5.2 through Fact-Aware RL, even without external tools
  • ⚡ Efficient Deployment: W4 quantization reduces memory to 26% of original; Gated Eagle3 speculative decoding achieves 96% speedup

📊 Performance

HealthBench & Hallucination Evaluation

HealthBench is OpenAI's authoritative medical benchmark, constructed by 262 practicing physicians from 60 countries, comprising 5,000 high-fidelity multi-turn clinical conversations.

Compared to Baichuan-M2, Baichuan-M3 improves by 28 percentage points on HealthBench-Hard, reaching 44.4 and surpassing GPT-5.2. It also ranks first on the HealthBench Total leaderboard.

For hallucination evaluation, we decompose long-form responses into fine-grained, verifiable atomic medical claims and validate each against authoritative medical evidence. Even in a tool-free setting, Baichuan-M3 achieves lower hallucination rate than GPT-5.2.

SCAN-bench Evaluation

SCAN-bench is our end-to-end clinical decision-making benchmark that simulates the complete clinical workflow from patient encounter to final diagnosis, evaluating models' high-fidelity clinical inquiry capabilities through three stations: History Taking, Ancillary Investigations, and Final Diagnosis.

Baichuan-M3 ranks first across all three core dimensions, outperforming the second-best model by 12.4 points in Clinical Inquiry.

📢 The SCAN-bench will be open-sourced soon. Stay tuned.

🔬 Technical Features

📖 For detailed technical information, please refer to: Tech Blog

SPAR: Segmented Pipeline Reinforcement Learning

To address reward sparsity and credit assignment challenges in long clinical interactions, we propose SPAR (Step-Penalized Advantage with Relative baseline): it decomposes clinical workflows into four stages—history taking, differential diagnosis, laboratory testing, and final diagnosis—each with independent rewards, combined with process-level rewards for precise credit assignment, driving the model to construct auditable and complete decision logic.

Fact-Aware Reinforcement Learning

By integrating factual verification directly into the RL loop, we build an online hallucination detection module that validates model-generated medical claims against authoritative medical evidence in real-time, supported by efficient caching mechanisms for online RL training. A dynamic reward aggregation strategy adaptively balances task learning and factual constraints based on the model's capability stage, significantly enhancing medical factual reliability without sacrificing reasoning depth.

Efficient Training and Inference

Adopts a three-stage multi-expert fusion training paradigm (Domain-Specific RL → Offline Distillation → MOPD), combined with Gated Eagle3 speculative decoding (96% speedup) and W4 quantization (only 26% memory) for efficient deployment.

🔧 Quick Start

from transformers import AutoTokenizer, AutoModelForCausalLM

model = AutoModelForCausalLM.from_pretrained("baichuan-inc/Baichuan-M3-235B-GPTQ-INT4", trust_remote_code=True)
tokenizer = AutoTokenizer.from_pretrained("baichuan-inc/Baichuan-M3-235B-GPTQ-INT4")

messages = [{"role": "user", "content": "I've been having headaches lately, especially worse in the afternoon. What should I do?"}]
text = tokenizer.apply_chat_template(
    messages,
    tokenize=False,
    add_generation_prompt=True,
    thinking_mode='on'
)
model_inputs = tokenizer([text], return_tensors="pt").to(model.device)

generated_ids = model.generate(
    **model_inputs,
    max_new_tokens=32768,
    temperature=0.6
)
response = tokenizer.decode(generated_ids[0][len(model_inputs.input_ids[0]):], skip_special_tokens=True)
print(response)

Deployment of INT4 Model

Create an OpenAI-compatible API endpoint using vllm>=0.11.0 (taking 4*H20(96G) as an example):

# vLLM
vllm serve baichuan-inc/Baichuan-M3-235B-GPTQ-INT4 --tensor-parallel-size 4 --reasoning-parser deepseek_r1

⚠️ Usage Notices

  1. Medical Disclaimer: For research and reference only; cannot replace professional medical diagnosis or treatment
  2. Intended Use Cases: Medical education, health consultation, clinical decision support
  3. Safe Use: Recommended under guidance of medical professionals

📄 License

Licens

Quoted from the model card on Hugging Face. The full card is behind the Hugging Face link above.

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