Model reference · open weights

Baichuan-M3-Q4_K_M

LLMs baichuan-inc Text gen 1 build Open weights 121 dl/mo

Baichuan-M3-Q4_K_M is an open-weight language model from baichuan-inc. Baichuan-M3-235B-Q4_K_M-GGUF (GGUF) weighs 144 GB; the smallest configuration that runs it is 4× L40S 48 GB.

  • Baichuan-M3 is a medical-enhanced large language model developed by baichuan-inc for text generation tasks, specifically designed to model clinical decision-making processes.
  • It supports English and Chinese and is licensed under the Apache 2.0 license.
  • The Q4_K_M quantized version reduces memory usage to 26% of the original size while maintaining high performance in medical benchmarks.

Summary of the baichuan-inc/Baichuan-M3-235B-Q4_K_M-GGUF model card, 2026-10-01

What it is

Released bybaichuan-inc
Released2026-02-06
VRAM144 GB for the weights

What it runs on

Memory and cards for Baichuan-M3-235B-Q4_K_M-GGUF (GGUF)

144 GBweights, file size
651 MBruntime overhead, at least

How much memory each request adds isn't estimated yet for this architecture. The weights need at least the cards below, plus room for the context.

CardWeights alone
RTX 3060 12 GB … H200 141 GB
11 smaller cards
does not fit
B200 180 GBfits
4× L40S 48 GB
split by layers (llama.cpp)
fits
2× RTX PRO 6000 Blackwell 96 GB
split by layers (llama.cpp)
fits
2× H200 141 GB
split by layers (llama.cpp)
fits
4× H100 80 GB
split by layers (llama.cpp)
fits
4× A100 80 GB
split by layers (llama.cpp)
fits

From the model card

What baichuan-inc says about Baichuan-M3-Q4_K_M

Read the model card

From Inquiry to Decision: Building Trustworthy Medical AI

🏥 Experience AI-Powered Medical Inquiry: ying.ai

🌟 Model Overview

Baichuan-M3 is Baichuan AI's new-generation medical-enhanced large language model, a major milestone following Baichuan-M2.

In contrast to prior approaches that primarily focus on static question answering or superficial role-playing, Baichuan-M3 is trained to explicitly model the clinical decision-making process, aiming to improve usability and reliability in real-world medical practice. Rather than merely producing "plausible-sounding answers" or high-frequency vague recommendations like "you should see a doctor soon," the model is trained to proactively acquire critical clinical information, construct coherent medical reasoning pathways, and systematically constrain hallucination-prone behaviors.

Core Highlights

  • 🏆 Surpasses GPT-5.2: Outperforms OpenAI's latest model across HealthBench, HealthBench-Hard, hallucination evaluation, and SCAN-bench, establishing a new SOTA in medical AI
  • 🩺 High-Fidelity Clinical Inquiry: The only model to rank first across all three SCAN-bench dimensions—Clinical Inquiry, Laboratory Testing, and Diagnosis
  • 🧠 Low Hallucination, High Reliability: Achieves lower hallucination rate than GPT-5.2 through Fact-Aware RL, even without external tools
  • ⚡ Efficient Deployment: W4 quantization reduces memory to 26% of original; Gated Eagle3 speculative decoding achieves 96% speedup

📊 Performance

HealthBench & Hallucination Evaluation

HealthBench is OpenAI's authoritative medical benchmark, constructed by 262 practicing physicians from 60 countries, comprising 5,000 high-fidelity multi-turn clinical conversations.

Compared to Baichuan-M2, Baichuan-M3 improves by 28 percentage points on HealthBench-Hard, reaching 44.4 and surpassing GPT-5.2. It also ranks first on the HealthBench Total leaderboard.

For hallucination evaluation, we decompose long-form responses into fine-grained, verifiable atomic medical claims and validate each against authoritative medical evidence. Even in a tool-free setting, Baichuan-M3 achieves lower hallucination rate than GPT-5.2.

SCAN-bench Evaluation

SCAN-bench is our end-to-end clinical decision-making benchmark that simulates the complete clinical workflow from patient encounter to final diagnosis, evaluating models' high-fidelity clinical inquiry capabilities through three stations: History Taking, Ancillary Investigations, and Final Diagnosis.

Baichuan-M3 ranks first across all three core dimensions, outperforming the second-best model by 12.4 points in Clinical Inquiry.

📢 The SCAN-bench will be open-sourced soon. Stay tuned.

🔬 Technical Features

📖 For detailed technical information, please refer to: Tech Blog

SPAR: Segmented Pipeline Reinforcement Learning

To address reward sparsity and credit assignment challenges in long clinical interactions, we propose SPAR (Step-Penalized Advantage with Relative baseline): it decomposes clinical workflows into four stages—history taking, differential diagnosis, laboratory testing, and final diagnosis—each with independent rewards, combined with process-level rewards for precise credit assignment, driving the model to construct auditable and complete decision logic.

Fact-Aware Reinforcement Learning

By integrating factual verification directly into the RL loop, we build an online hallucination detection module that validates model-generated medical claims against authoritative medical evidence in real-time, supported by efficient caching mechanisms for online RL training. A dynamic reward aggregation strategy adaptively balances task learning and factual constraints based on the model's capability stage, significantly enhancing medical factual reliability without sacrificing reasoning depth.

Efficient Training and Inference

Adopts a three-stage multi-expert fusion training paradigm (Domain-Specific RL → Offline Distillation → MOPD), combined with Gated Eagle3 speculative decoding (96% speedup) and W4 quantization (only 26% memory) for efficient deployment.

🔧 Quick Start

For deploying the Q4_K_M quantized model, you can use llama.cpp or ollama, please visit their website to get the specific operational steps for deploying the model.

⚠️ Usage Notices

  1. Medical Disclaimer: For research and reference only; cannot replace professional medical diagnosis or treatment
  2. Intended Use Cases: Medical education, health consultation, clinical decision support
  3. Safe Use: Recommended under guidance of medical professionals

📄 License

Licensed under the Apache License 2.0. Research and commercial use permitted.

🤝 Acknowledgements

  • Base Model: Qwen3
  • Training Framework: verl
  • Inference Engines: vLLM, SGLang

Thank you to the open-source community. We commit to continuous contribution and advancement of healthcare AI.

📞 Contact Us

Advancing Medical AI from "Answering Correctly" to "Supporting Decisions"

📚 Citation

@article{Baichuan-M3 Technical Report,
  title={Baichuan-M3: Modeling Clinical Inquiry for Reliable Medical Decision-Making},
  author={Baichuan-M3 Team: Chengfeng Dou, Fan Yang, Fei Li, Jiyuan Jia, Qiang Ju, Shuai Wang, Tianpeng Li, Xiangrong Zeng, Yijie Zhou, Hongda Zhang, Jinyang Tai, Linzh

Quoted from the model card on Hugging Face. The full card is behind the Hugging Face link above.

How it works

How language models work

Your prompttext / messagesTransformerattention over tokensNext-token loopgenerate + streamResponsetext · tool callsA language model reads your tokens and predicts the next one, again and again, streaming the reply back.
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