Model reference · open weights
medgemma-1.5 is an open-weight language model from Google. medgemma-1.5-4b-it-GGUF (GGUF) weighs 2.5 GB; the smallest configuration that runs it is RTX 3060 12 GB.
Summary of the google/medgemma-1.5-4b-it model card, 2026-10-01. The estimate below is for another build of the family.
What it is
| Released by | |
|---|---|
| Released | 2026-01-07 |
| Parameters | 4.3B |
| VRAM | 2.5 GB for the weights |
What it runs on
How much memory each request adds isn't estimated yet for this architecture. The weights need at least the cards below, plus room for the context.
| Card | Weights alone |
|---|---|
| RTX 3060 12 GB | fits |
| RTX 4060 Ti 16 GB | fits |
| RTX 3090 24 GB | fits |
| RTX 4090 24 GB | fits |
| RTX 5090 32 GB | fits |
| L40S 48 GB | fits |
| A100 80 GB | fits |
| H100 80 GB | fits |
| RTX PRO 6000 Blackwell 96 GB | fits |
| DGX Spark (GB10) 128 GB unified | fits |
| H200 141 GB | fits |
| B200 180 GB | fits |
Builds
| Build | Params | Precision | Weights | Smallest setup |
|---|---|---|---|---|
| medgemma-1.5-4b-it ↗ | 4.3B | BF16 | 8.6 GB | RTX 3060 12 GB |
| medgemma-1.5-4b-it-GGUF (above) ↗ packaged by unsloth 26 builds: IQ1_S 1.2 GB … BF16 7.8 GB |
— | GGUF | 2.5 GB | RTX 3060 12 GB |
From the model card
Note: This card describes MedGemma 1.5, which is only available as a 4B multimodal instruction-tuned variant. For information on MedGemma 1 variants, refer to the MedGemma 1 model card.
Model documentation: MedGemma
Resources:
Model on Google Cloud Model Garden: MedGemma
Models on Hugging Face: Collection
Concept applications built using MedGemma: Collection
License: The use of MedGemma is governed by the Health AI Developer Foundations terms of use. MedGemma has not been evaluated or optimized for multi-turn applications.
MedGemma's training may make it more sensitive to the specific prompt used than Gemma 3.
When adapting MedGemma developer should consider the following:
License: The use of MedGemma is governed by the Health AI Developer Foundations terms of use.
Support channels
Author: Google
This section describes the specifications and recommended use of the MedGemma model.
MedGemma is a collection of Gemma 3 variants that are trained for performance on medical text and image comprehension. Developers can use MedGemma to accelerate building healthcare-based AI applications.
MedGemma 1.5 4B is an updated version of the MedGemma 1 4B model.
MedGemma 1.5 4B expands support for several new medical imaging and data processing applications, including:
In addition to these new features, MedGemma 1.5 4B delivers improved accuracy on medical text reasoning and modest improvement on standard 2D image interpretation compared to MedGemma 1 4B.
MedGemma utilizes a SigLIP image encoder that has been specifically pre-trained on a variety of de-identified medical data, including chest X-rays, dermatology images, ophthalmology images, and histopathology slides. The LLM component is trained on a diverse set of medical data, including medical text, medical question-answer pairs, FHIR-based electronic health record data, 2D and 3D radiology images, histopathology images, ophthalmology images, dermatology images, and lab reports for document understanding.
MedGemma 1.5 4B has been evaluated on a range of clinically relevant benchmarks to illustrate its baseline performance. These evaluations are based on both open benchmark datasets and internally curated datasets. Developers are expected to fine-tune MedGemma for improved performance on their use case. Consult the Intended use section for more details.
MedGemma is optimized for medical applications that involve a text generation component. For medical image-based applications that do not involve text generation, such as data-efficient classification, zero-shot classification, or content-based or semantic image retrieval, the MedSigLIP image encoder is recommended. MedSigLIP is based on the same image encoder that powers MedGemma 1 and MedGemma 1.5.
The following are some example code snippets to help you quickly get started running the model locally on GPU.
Note: If you need to use the model at scale, we recommend creating a production version using Model Garden. Model Garden provides various deployment options and tutorial notebooks, including specialized server-side image processing options for efficiently handling large medical images: Whole Slide Digital Pathology (WSI) or volumetric scans (CT/MRI) stored in Cloud DICOM Store or Google Cloud Storage (GCS).
First, install the Transformers library. Gemma 3 is supported starting from transformers 4.50.0.
$ pip install -U transformers
Next, use either the pipeline wrapper or the transformer API directly to send a chest X-ray image and a question to the model.
Note that CT, MRI and whole-slide histopathology images require some pre-processing; see the CT and [WSI](https://github.com/
Quoted from the model card on Hugging Face. The full card is behind the Hugging Face link above.
How it works