Model reference · open weights

Intern-S2

LLMs internlm Vision + text 5 builds Open weights 932 dl/mo

Intern-S2 is an open-weight language model from internlm. Intern-S2-Preview-397B (BF16) weighs 810 GB; the smallest configuration that runs it is 8× H200 141 GB.

  • Intern-S2-Preview is a 36.1B parameter multimodal foundation model developed by internlm for image-text-to-text tasks.
  • It is designed for scientific applications, featuring capabilities in material crystal structure generation, time-series modeling, and agentic workflows.
  • The model is released under the Apache-2.0 license.

Summary of the internlm/Intern-S2-Preview model card, 2026-10-01. The estimate below is for another build of the family.

What it is

Released byinternlm
Released2026-05-15
Parameters36.1B
VRAM810 GB for the weights

What it runs on

Memory and cards for Intern-S2-Preview-397B (BF16)

810 GBweights, file size
31 MBcache per 1K tokens
384 MBfixed state per request
3.2 GBruntime overhead, at least
262,144 tokenscontext max
CardRequests at onceContext maxMemory
8K each32K each
RTX 3060 12 GB … 8× A100 80 GB
14 smaller cards
———
8× H200 141 GB
tensor parallel
14244all 256K138 GB a card
8× B200 180 GB
tensor parallel
333105all 256K176 GB a card
Memory needed at each load
Requests at once8K tokens each32K tokens each
1814 GB815 GB
5817 GB821 GB
8819 GB825 GB
16824 GB836 GB
32834 GB858 GB
64854 GB903 GB

One card, with vLLM's small-card settings.

Builds

Sizes, precisions & builds

BuildParamsPrecisionWeightsSmallest setup
Intern-S2-Preview ↗ 36.1BBF16 73.2 GBA100 80 GB
Intern-S2-Preview-FP8 ↗ 36.1BFP8 38.8 GBL40S 48 GB
Intern-S2-Preview-397B (above) ↗ 404.1BBF16 810 GB8× H200 141 GB
Intern-S2-Preview-397B-FP8 ↗ 403.4BFP8 408 GB4× H200 141 GB
Intern-S2-397B ↗ 403.4BBF16 807 GB8× H200 141 GB

From the model card

What internlm says about Intern-S2

Read the model card

Intern-S2-Preview

💻Github Repo • 🤗Model Collections • 💬Online Chat

Introduction

We introduce Intern-S2-Preview, an efficient 35B scientific multimodal foundation model. Beyond conventional parameter and data scaling, Intern-S2-Preview explores task scaling: increasing the difficulty, diversity, and coverage of scientific tasks to further unlock model capabilities.

By extending professional scientific tasks into a full-chain training pipeline from pre-training to reinforcement learning, Intern-S2-Preview achieves performance comparable to the trillion-scale Intern-S1-Pro on multiple core professional scientific tasks, while using only 35B parameters (continued pretrained from Qwen3.5). At the same time, it maintains strong general reasoning, multimodal understanding, and agent capabilities.

Features

  • Scientific task scaling with full-chain training. Intern-S2-Preview scales hundreds of professional scientific tasks from pre-training to RL, enabling strong performance across multiple specialized domains at only 35B parameters. It further strengthens spatial modeling for small-molecule structures and introduces real-valued prediction modules, making it the first open-source model with both material crystal structure generation capability and strong general capabilities.

  • Enhanced agent capabilities for scientific workflows. Intern-S2-Preview significantly improves agentic abilities over the previous generation, achieving strong results on multiple scientific agent benchmarks.

  • Efficient RL reasoning with MTP and CoT compression. During RL, Intern-S2-Preview adopts shared-weight MTP with KL loss to reduce the mismatch between training and inference behavior, substantially improving MTP accept rate and token generation speed. It also introduces CoT compression techniques to shorten responses while preserving strong reasoning capability, achieving improvements in both performance and efficiency.

  • Upgraded time-series Modeling for better physical signal representation; supports long, heterogeneous time-series (10^0–10^6 points).

Performance

We evaluate the Intern-S2-Preview on various benchmarks, including general datasets and scientific datasets. We report the performance comparison with the recent VLMs and LLMs below.

Note: Underline means the best performance among open-sourced models, Bold indicates the best performance among all models.

We use the OpenCompass and VLMEvalKit to evaluate all models. For text reasoning benchmarks, Intern-S2-Preview is evaluated with a maximum inference length of 128K tokens, while for multimodal benchmarks, it is evaluated with a maximum inference length of 64K tokens.

Quick Start

Sampling Parameters

We recommend using the following hyperparameters to ensure better results

top_p = 0.95
top_k = 50
min_p = 0.0
temperature = 0.8

Serving

Intern-S2-Preview can be deployed using any of the following LLM inference frameworks:

  • LMDeploy
  • vLLM
  • SGLang

Detailed deployment examples for these frameworks are available in the Model Deployment Guide.

Advanced Usage

Tool Calling

Tool Calling lets the model extend its capabilities by invoking external tools and APIs. The example below shows how to use it to fetch the latest weather forecast via an OpenAI-compatible API (based on lmdeploy api server).


from openai import OpenAI
import json

def get_current_temperature(location: str, unit: str = "celsius"):
    """Get current temperature at a location.

    Args:
        location: The location to get the temperature for, in the format "City, State, Country".
        unit: The unit to return the temperature in. Defaults to "celsius". (choices: ["celsius", "fahrenheit"])

    Returns:
        the temperature, the location, and the unit in a dict
    """
    return {
        "temperature": 26.1,
        "location": location,
        "unit": unit,
    }

def get_temperature_date(location: str, date: str, unit: str = "celsius"):
    """Get temperature at a location and date.

    Args:
        location: The location to get the temperature for, in the format "City, State, Country".
        date: The date to get the temperature for, in the format "Year-Month-Day".
        unit: The unit to return the temperature in. Defaults to "celsius". (choices: ["celsius", "fahrenheit"])

    Returns:
        the temperature, the location, the date and the unit in a dict
    """
    return {
        "temperature": 25.9,
        "location": location,
        "date": date,
        "unit": unit,
    }

def get_function_by_name(name):
    if name == "get_current_temperature":
        return get_current_temperature
    if name == "get_temperature_date":
        return get_temperature_date

tools = [{
    'type': 'function',
    'function': {
        'name': 'get_current_temperature',
        'description': 'Get current temperature at a location.',
        'parameters': {
            'type': 'object',
            'properties': {
                'location': {
                    'type': 'string',
                    'description': 'The location to get the temperature for, in the format \'City, State, Country\'.'
                },
                'unit': {
                    'type': 'string',
                    'enum': [
                        'celsius',
                        'fahrenheit'
                    ],
                    'description': 'The unit to return the temperature in. Defaults to \'celsius\'.'
                }
            },
            'required': [
                'location'
            ]
        }
    }
}, {
    'type': 'function',
    'function': {
        'name': 'get_temper

Quoted from the model card on Hugging Face. The full card is behind the Hugging Face link above.

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